MP4: MICROCYTOSIS IN PERNICIOUS ANEMIA WITHOUT IRON DEFICIENCY OR THALASSEMIA TRAIT
نویسندگان
چکیده
منابع مشابه
Differential Diagnosis of Microcytic Anemia, Thalassemia or Iron Deficiency Anemia: A Diagnostic Test Accuracy Meta-Analysis
We evaluated the most common indices to compare their sensitivity and specificity to introduce the most sensitive and specific index. We systematically searched five international indexing databases up to Dec 2018. For each index, we measured the diagnostic odds ratio (DOR), as well as summary ROC (SROC) curve which was used to compare the performance of each index. Deeks̕ tests of all discrimin...
متن کاملAutomated measurement of red blood cell microcytosis and hypochromia in iron deficiency and beta-thalassemia trait.
Some routine red blood cell (RBC) measurements and indexes (count, mean volume, volume dispersion, and mean hemoglobin [HGB] concentration) can be used to differentiate iron deficiency from heterozygous beta-thalassemia. A number of formulas that incorporate two or more of these measurements have been described to amplify such differences. The H*1 hematology analyzer directly measures volume an...
متن کاملErythrocyte Catalase Activity in More Frequent Microcytic Hypochromic Anemia: Beta-Thalassemia Trait and Iron Deficiency Anemia
Most common microcytic hypochromic anemias are iron deficiency anemia (IDA) and β-thalassemia trait (BTT), in which oxidative stress (OxS) has an essential role. Catalase causes detoxification of H2O2 in cells, and it is an indispensable antioxidant enzyme. The study was designed to measure erythrocyte catalase activity (ECAT) in patients with IDA (10) or BTT (21), to relate it with thalassemia...
متن کاملEvaluation of Twenty Four Discriminant Indices for Differentiating Beta-Thalassemia Trait from Iron Deficiency Anemia in Egyptians
Background: Many Red Blood Cell (RBC) indices have been developed based on mathematical formulae to discriminate beta-thalassemia trait (βTT) from iron deficiency anemia (IDA). The latter two conditions represent the most common causes of microcytic hypochromic anemia in Egypt. This study aimed To evaluate the diagnostic reliability of 24 published discriminant indices for differentiating βTT f...
متن کاملIron-deficiency anemia and thalassemia trait differentiated by simple hematological tests and serum iron concentrations.
The diagnostic value of common hematology tests in differentiating between thalassemia trait and iron-deficiency anemia (IDA) was assessed. Serum iron concentration was included in a second stage of the diagnostic model and its predictive contribution was determined. After applying discriminant analysis to the data, minimization of Wilks's lambda (lambda) criterion was used to select the best p...
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ژورنال
عنوان ژورنال: Journal of Investigative Medicine
سال: 2016
ISSN: 1081-5589,1708-8267
DOI: 10.1136/jim-2016-000080.16